Anti-beta 2 glycoprotein I antibodies in centenarians
نویسندگان
چکیده
منابع مشابه
Anti-beta 2 glycoprotein I antibodies in centenarians.
BACKGROUND Non-organ-specific autoantibodies are present in centenarians without evidence of autoimmune diseases but conflicting or no data on anti-phospholipid and anti-phospholipid binding proteins were reported. OBJECTIVE To investigate the presence and antigen specificity of anti-phospholipid and anti-phospholipid binding proteins in centenarians. METHODS Seventy-seven centenarians, 70 ...
متن کاملAntiphospholipid, anti-beta 2-glycoprotein-I and anti-oxidized-low-density-lipoprotein antibodies in antiphospholipid syndrome.
Antiphospholipid antibodies (aPL), anti-beta 2-glycoprotein I (anti-beta 2-GPI) and anti-oxidized-low-density lipoprotein (LDL) antibodies are all implicated in the pathogenesis of antiphospholipid syndrome. To investigate whether different autoantibodies or combinations thereof produced distinct effects related to their antigenic specificities, we examined the frequencies of antiphospholipid s...
متن کاملSignificance of anticardiolipin and anti-beta(2)-glycoprotein I antibodies in lupus nephritis.
OBJECTIVE To investigate whether anticardiolipin (aCL) and anti-beta(2)-glycoprotein I (anti-beta(2)GPI) antibodies are associated with lupus nephritis (group II patients), and whether there are differences in the prevalence of these two autoantibodies between group II patients and patients with non-nephritis SLE (group I) and primary antiphospholipid syndrome (PAPS) patients (group III). MET...
متن کاملHigh avidity anti-beta 2-glycoprotein I antibodies in patients with antiphospholipid syndrome.
OBJECTIVE To evaluate avidity of IgG anti-beta 2-glycoprotein I antibodies (anti-beta2-GPI) in patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) in relation to thrombosis, and to demonstrate a possible affinity maturation of IgG anti-beta 2-GPI during the disease course. METHODS 64 sera from 32 patients (18 with primary or secondary APS, 14 with SLE without ...
متن کاملAnti-beta 2-glycoprotein I, antiprothrombin antibodies, and the risk of thrombosis in the antiphospholipid syndrome.
The association of antiphospholipid antibodies with thrombosis and obstetric events defines the antiphospholipid syndrome. A recent systematic review of the literature showed lupus anticoagulants to be risk factors of thrombosis, independent of the type and site of the event, the presence of systemic lupus erythematosus, and the laboratory methods used to detect them. Anticardiolipin antibodies...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Experimental Gerontology
سال: 2004
ISSN: 0531-5565
DOI: 10.1016/j.exger.2004.08.003